Immunopathogenesis in Trypanosoma cruzi infection: a role for suppressed macrophages and apoptotic cells
During Trypanosoma cruzi infection, macrophages phagocytose parasites and remove apoptotic cells 4 Thrive through efferocytosis.While macrophage 1 (M1) produces proinflammatory cytokines and NO and fights infection, M2 macrophages are permissive host cells that express arginase 1 and play a role in tissue repair.The regulation of M1 and M2 phenotyp